Studies
What is a Study?*Tigist Y Tamir 1,2,3,6, Shreya Chaudhary 1,6, Annie X Li 1,6, Sonia E Trojan 1,4,6 3 , Cameron T Flower 1,2,5,6, Paula Vo 7 , Yufei Cui 1,3,6, Jeffrey C Davis1,4,6, Rachit S Mukkamala 1,3,6 4 , Francesca N Venditti 1,6, Alissandra L Hillis 8 , Alex Toker 8 , Matthew G Vander Heiden 1,2,4,6,7 5 , Jessica B Spinelli 9 , Norman J Kennedy 9 , Roger J Davis 9 , and *Forest M White 1,2,3,5,6
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DOI: https://www.biorxiv.org/content/10.1101/2024.08.28.609894v1.full
Abstract: Coordination of adaptive ...
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm

https://www.biorxiv.org/content/10.1101/2025.01.10.632378v1
Abstract: Lung fibrosis, characterized by chronic and progressive scarring, has no cure. Hallmarks are the accumulation of myofibroblasts and extracellular matrix, as well as vascular remodeling. The crosstalk between myofibroblasts and vasculature is poorly understood, with ...
Marie Floryan, Elena Cambria, Adriana Blazeski, Mark F. Coughlin, Zhengpeng Wan, Giovanni Offeddu, Vinayak Vinayak, Aayush Kant, Vivek Shenoy, Roger D. Kamm

DOI:
Abstract: The incorporation of a functional perfusable microvascular network (MVN) is a common requirement for most organ on-chip-models. Long-term perfusion of MVNs is often required for the maturation of organ phenotypes and disease pathologies and to model the transport of cells and drugs entering ...
Submitter: Demo Demo
Investigation: MetNet
Assays: All Metadata, Cell Extraction - Metadata, Cytokine Luminex - Data Linked, Gene Expression Analysis - Data Linked, Library Prep - Metadata, MVN Imaging Analysis - Data Linked, Mass Spectrometry Proteomics - Data Linked, Microfluidic Network Formation - Metadata, Microfluidic Network Imaging - Data Linked, Proteomics Analysis - Data Linked, RNA Extraction - Metadata, Short Read Sequencing - Data Linked
Nina Gubina, Lindsay B. Volk, Anna Dormitzer, Emily Michelsen, Lee J. Pribyl, Joshua J. Corrigan, Esha Dalvie, Amanda L. Armijo, Nicolette A. Bugher, Kayla Shonvisky, Monét Norales, Desiree L. Plata, Bevin P. Engelward, Robert G. Croy, John M. Essigmann, Bogdan I. Fedeles

DOI:
Abstract: N-Nitrosodimethylamine (NDMA) is an animal and probable human carcinogen. Here DNA adduct and high-resolution mutational spectra were correlated following administration of ...
Submitter: Demo Demo
Investigation: SRP
Assays: All Metadata, Chemical Challenge - Metadata, DNA Extraction - Metadata, ELISA - Data Linked, GPT Assay - Data Linked, Library Prep - Metadata, Mass Spectrometry - Data Linked, Mutational Spectra Analysis - Data Linked, PCR - Data Linked, RNA Extraction - Metadata, RaDR - Data Linked, Short Read Sequencing - Data Linked, Tissue Collection - Metadata
The data / metadata will be available ** online** at the time of paper acceptance. If you would like access prior to acceptance, please reach out to Lindsay Volk: (lvolk@mit.edu)