Studies
What is a Study?
Nina Gubina, Lindsay B. Volk, Anna Dormitzer, Emily Michelsen, Lee J. Pribyl, Joshua J. Corrigan, Esha Dalvie, Amanda L. Armijo, Nicolette A. Bugher, Kayla Shonvisky, Monét Norales, Desiree L. Plata, Bevin P. Engelward, Robert G. Croy, John M. Essigmann, Bogdan I. Fedeles
DOI:
Abstract: N-Nitrosodimethylamine (NDMA) is an animal and probable human carcinogen. Here DNA adduct and high-resolution mutational spectra were correlated following administration of ...
Submitter: Demo Demo
Investigation: SRP
Assays: All Metadata, Chemical Challenge - Metadata, DNA Extraction - Metadata, ELISA - Data Linked, GPT Assay - Data Linked, Library Prep - Metadata, Mass Spectrometry - Data Linked, Mutational Spectra Analysis - Data Linked, PCR - Data Linked, RNA Extraction - Metadata, RaDR - Data Linked, Short Read Sequencing - Data Linked, Tissue Collection - Metadata
The data / metadata will be available ** online** at the time of paper acceptance. If you would like access prior to acceptance, please reach out to Lindsay Volk: (lvolk@mit.edu)
Zhewen Guo, Haosheng Feng, Timothy Swager
DOI: https://pubs.acs.org/doi/10.1021/acssensors.4c02462
Abstract: Herein, we present the development and evaluation of a molecularly imprinted polymer (MIP) sensor for the sensitive and selective detection of N-nitrosodimethylamine (NDMA) in aqueous environments. MIP coatings over electrochemically active electrodes enable NDMA detection with a notably low detection limit of 1.16 ppb. Our findings demonstrate that the ...
Auto-created study: Colorimetric Detection of Aqueous N-Nitrosodimethylamine via Photonitrosation of a Naphtholsulfonate Indicator
Submitter: Demo Demo
Investigation: SRP
Assays: Chemical Synthesis - Metadata, Imaging - Data Linked, Nuclear Magnetic Resonance - Data Linked, Nuclear Magnetic Resonance Analysis - Data Linked, Single-crystal X-ray Crystallography - Data Linked, UV-Vis Spectroscopy - Data Linked, UV-Vis Spectroscopy Analysis - Data Linked
Jing Ge, Le P. Ngo, Simran Kaushal, Ian J. Tay, Elina Thadhani, Jennifer E. Kay, Patrizia Mazzucato, Danielle N. Chow, Jessica L. Fessler, David M. Weingeist, Robert W. Sobol, Leona D. Samson, Scott R. Floyd, Bevin P. Engelward,*
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8439179/
DNA damage can be cytotoxic and mutagenic, and it is directly linked to aging, cancer, and other diseases. To counteract the deleterious effects of DNA damage, cells have ...
Michelle Chen, Elliot I. Corless, Bevin P. Engelward, Timothy M. Swager
Link to Paper: https://pubs.acs.org/doi/full/10.1021/acsomega.4c03959
Agglutination of liquid Janus emulsions creates optical signals that can be detected and quantified. This study reports the detection and quantitation of Interleukin-6 (IL-6) using emulsions functionalized at the water-organic interface with engineered hyperthermophilic affinity proteins (rcSso7d) derived from ...
Submitter: Demo Demo
Investigation: SRP
Assays: Agglutination Assay - Data Linked, Chemical Synthesis - Metadata, Fourier Transform Infrared Spectroscopy - Data Linked, Gel Permeation Chromatography - Data Linked, Nuclear Magnetic Resonance Spectroscopy - Data Linked, Nuclear Magnetic Resonance Spectroscopy Analysis - Data Linked, Pendant Drop Tensiometry - Data Linked
